Complete Information on Dubowitz syndrome with Treatment and Prevention
Dubowitz syndrome is a genetic disorder defined by slow growth, a characteristic facial appearance, and a small head. Although the exact pathology of Dubowitz syndrome is not yet known, it is almost certain that it has a genetic component.
It is classified as an autosomal recessive disease, one that can be passed down through the generations. Several cases point to dubowitz syndrome occurring in monozygotic twins, siblings as well as cousins. However, although it is a recessive trait that can be expressed to cause disorder symptoms, there has been found to be a variation in the phenotypic expression. It has been found that dubowitz syndrome is accompanied by a deficiency in the growth hormone. This is apparent in the stunted growth of individuals with this disorder. A deficiency in growth hormone may be caused by malformations of the hypothalamus or pituitary gland during development or damage to the pituitary.